• Hollowed out area that forms in wall because of erosion of a circumscribed area of mucous membrane
• Occurs most in duodenum

Possible causes:

• Infection w/H.PYLORI
• Use of NSAIDs
• People w/blood type O
• Chronic pulmonary disease

Manifestations:

• Dull/Gnawing pain
• Burning sensation in midepigastrium or back
• Gastric- pain after eating
• Duodenal- pain 2-3hrs after meals, relief of pain after eating or after taking antacid
• Pyrsosi (Heartburn)

Diagnostic finding:

• Upper endoscopy

Management:

• Antibio + PPI +Bismuth salts (Eradicate H.PYLORI)
• Therapy 10-14 days
• Triple therapy