• Obstruction to flow of pancreatic enzymes resulting in inflammation of pancreas
• Alcoholic pancreatitis (Chronic)
• Self digestion by an enzyme- Trypsin

Manifestations:

• Severe abdominal pain and N/V!!
• Acute epigastric pain, steady & severe, umbilical area radiates to back
• Pain greater when lying supine
• Leukocytosis, hyperglycemia, elev. amylase & lipase
• Grey Turner- bluish discoloration over flank area (accum. of blood in that area)
• Cullen Sign- bluish discoloration around umbilicus (sign of bleeding)

Management:

• Semi-fowlers
• Freq. change in position= prevent atelectasis
• NPO stat
• IV hydration
• Peritoneal lavage
• Endoscopic transduodenal sphincterotomy remove retained gallstones
• Pancreatic enzyme replacement w/pancrelipase (Viokase) to manage ab pain * reduce steatorrhea
• No alcohol
• Low cholesterol