Rapid acting: Onset Peak Duration

• lispro (Humalog) 10–15 min 1 h 2–4 h
• aspart (NovoLog) 5–15 min 40–50 min 2–4 h
• glulisine (Apidra) 5–15 min 30–60 min 2 h

Short acting:

• regular (Humalog R, Novolin R, Iletin II Regular)

1½–1 h 2–3 h 4–6 h

Intermediate acting:

• NPH (neutral protamine Hagedorn)

2–4 h 4–12 h 16–20 h

(Humulin N, Iletin II Lente, Iletin II NPH, Novolin N

) 3–4 h 4–12 h 16–20 h

Very long acting:

• glargine (Lantus)

1 h Continuous (no peak) 24 h