homophobia
biphobia
transphobia
exclusionist bullshit (this includes ace exclusion, transmed bullshit, and mockery) (I may just mute you instead if its not super malicious)
racism
conservative nonsense
shipping drama, both sides (they're fictional please shut up)
you were being condescending over something I take personally (an 'okay, asshole' moment)
I find you annoying (more likely to mute)
I have forgotten about the mute function
one of my mutuals was spamming your stuff and I lost my patience (not personal. sorry)
in general blocking is something I use because it's the easiest way to keep my timeline as clean as I'd like. if you're not a complete bastard then its really not that deep
I do not normally softblock. unfollowing me is your business and your prerogative