- The Iron Lady (2011) Margaret Thatcher
- ✔ It’s Complicated (2009) Jane
- Fantastic Mr. Fox (2009) (voice) Mrs. Fox
- ✔ Julie & Julia (2009) Julia Child
- ✔ Doubt (2008/I) Sister Aloysius Beauvier
- ✔ Mamma Mia! (2008) Donna Sheridan
- ✔ Lions for Lambs (2007) Janine Roth
- ✔ Rendition (2007) Corrine Whitman
- ✔ Evening (2007) Lila Ross
- Dark Matter (2007/I) Joanna Silver
- The Ant Bully (2006) (voice) Queen
- ✔ The Devil Wears Prada (2006) Miranda Priestly
- The Music of Regret (2006) The Woman
- ✔ A Prairie Home Companion (2006) Yolanda Johnson
- ✔ Prime (2005) Lisa Metzger
- Lemony Snicket’s A Series of Unfortunate Events (2004) Aunt Josephine
- ✔ The Manchurian Candidate (2004) Eleanor Shaw
- ✔ The Hours (2002) Clarissa Vaughan
- ✔ Adaptation. (2002) Susan Orlean
- Artificial Intelligence: AI (2001) (voice) Blue Mecha
- ✔ Music of the Heart (1999) Roberta Guaspari
- Chrysanthemum (1999) (voice) Narrator
- ✔ One True Thing (1998) Kate Gulden
- ✔ Dancing at Lughnasa (1998) Kate ‘Kit’ Mundy
- ✔ First Do No Harm (1997) (TV) Lori Reimuller
- ✔ Marvin’s Room (1996) Lee
- Before and After (1996) Dr. Carolyn Ryan
- ✔ The Bridges of Madison County (1995) Francesca Johnson
- ✔ The River Wild (1994) Gail Hartman
- ✔ The House of the Spirits (1993) Clara del Valle Trueba
- ✔ Death Becomes Her (1992) Madeline Ashton
- Defending Your Life (1991) Julia
- ✔ Postcards from the Edge (1990) Suzanne Vale
- ✔ She-Devil (1989) Mary Fisher
- Rabbit Ears: The Fisherman and His Wife (1989) (V) Storyteller
- ✔ Evil Angels (1988) Lindy Chamberlain (A Cry In The Dark)
- The Tailor of Gloucester (1988) Narrator
- Ironweed (1987) Helen Archer
- Ears: The Tale of Peter Rabbit (1987) (voice) Storyteller
- Rabbit Ears: The Tale of Mr. Jeremy Fisher (1987) (voice)
- ✔ Heartburn (1986) Rachel Samstat
- Plenty (1985) Susan Traherne
- ✔ Out of Africa (1985) Karen Blixen
- ✔ Falling in Love (1984) Molly Gilmore
- ✔ Silkwood (1983) Karen Silkwood
- ✔ Sophie’s Choice (1982) Sophie Zawistowski
- Still of the Night (1982) Brooke Reynolds
- Alice at the Palace (1982) (TV) Alice
- The French Lieutenant’s Woman (1981) Sarah / Anna
- Kiss Me, Petruchio (1981) (TV) Katherine
- ✔ Kramer vs. Kramer (1979) Joanna Kramer
- The Seduction of Joe Tynan (1979) Karen Traynor
- Uncommon Women… and Others (1979) (TV) Leilah
- ✔ Manhattan (1979) Jill
- ✔ The Deer Hunter (1978) Linda
- Julia (1977) Anne Marie
- The Deadliest Season (1977) (TV) Sharon Miller
- Secret Service (1977) (TV) Edith Varney
- Everybody Rides the Carousel (1975) (voice)
dec 31 2011 ∞
dec 31 2011 +
dec 31 2011 +