For 05.01.19 (10.01.19 latest) Remember mechanism and experimental images

• Antibiotics and antibiotic resistance
  • Add images
• Nalidixic acid/quinolones and resistance
  • General quinolone info
  • How does bacterial mechanism work normally?
  • How do quinolones affect mechanism?
  • Action (DNA gyrase and topo IV)
  • Most common resistance mechanism
• Genetic screen details
  • Show ydgJ growth on nal (compared to control)
  • How to reference unpublished?
• ydgJ identification
  • Find as much general info as possible
  • From oxidoreductase genetics
  • Include homology model?
• Oxidoreductases
  • Function
  • General info on different families
  • Conserved features/domains
  • Focus on one most homologous to ydgJ
  • How could they confer resistance?
  • Suggestion for ydgJ mechanism
• State aim of project in context of background given
  • Interactome of ydgJ as showed resistance to nal in screen
  • Interacting proteins could give more info on how ydgJ resistance mechanism works