nucleotides
- are monomers that make up nucleic acids
- are made of pentose sugar, a phosphate group, and a nitrogen base
- nucleoside consists of only one pentose sugar and nitrogen-containing base
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- carbon numbering matters when speaking about nucleic acids
from the oxygen go clockwise
ribose - obeys carbon perfectly
nucleotides join together polymerize in condensation reactions, forming phosphodiester links
H from OH and the OH from the third 3' 3 prime (idk the third something) tp create a phosphodiester linkage
nucleic acids go in a 5' to 3' pattern -
- bases may be either pyrimidine single ring or purine two fused rings
- purines always match with pyrimidines
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- identity of the base determines the identity of nucleotide
- RNA has uracil U instead of thymine
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- A pairs with T/U and C pairs with G
- C and G is a stronger bond
- (CGI {no I} and @u, at you) "CGI is better than u"
DNA and RNA purified substances can be made to form crystals. x-ray passed through it, positions of atoms is inferred from the pattern of diffraction