I add to this list as I discover characters

My favorite sillies:

• Dr. Steel
• Dr. Caligosto Loboto (Psychonauts)
• Dr. Poison (Wonder Woman DC)
• Dr. Kasukabe (Dorohedoro)
• Dr. Zomboss (PVZ)
• Dr. Two Brains (Wordgirl)
• The Doctor (Superjail)
• Dr. Stankfoot (Zevo-3)
• Dr. Octavius Brine (Penguins of Madagascar)
• Dr. Otto Octavius (Spiderman 2)
• Herman Carter (Dead By Daylight)
• Cioccolata (Jojo's Bizzare Adventure)
• Herbert West (Re-Animator)
• The Medic (TF2)
• Nathan Wallace (REPO! The Genetic Opera)

Everyone else:

• Dr. Killjoy (The Suffering)
• Dr. J.S. Steinman (Bioshock 1)
• The Lobe (Freakazoid!)
• Franny K. Stein (her books)
• Dr. Franken Stein (Soul Eater)
• Pop Fizz (Skylanders)
• Dr. Jason Woodrue (Batman & Robin)
• Hugo Strange (DC - Batman Villian)
• Dr. Eggman (Sonic Franchise)
• Dr. Junkenstein (Overwatch Seasonal Event)
• Singed (Arcane - Leauge of Legends)
• Dr. Frank-N-Furter (The Rocky Horror Picture Show)
• Frederick Frankenstein (Young Frankenstein)
• C.A. Rotwang (Metropolis)
• Seth Brundle (The Fly)
• Dexter (Dexters Labratory)
• Prof. Boxmore (OK.KO.)
• Brain (Animaniacs - Pinky and the Brain)
• Dr. Phage (Awful Hospital)
• Dr. Mizer (Awful Hospital)
• Romeo (PJ Masks)
• Victor Frankenstein (Monster high)
• Dr. Horrible (Dr. Horrible's Sing-Along Blog)
• Jeffrey Franken (Frankenhooker)
• Dr. Weird (Aqua Teen Hunger Force)