canon-related comfort characters:

• Sans & Papyrus - Undertale
• Alchemist Cookie - Cookie Run
• Adventurer Cookie - Cookie Run
• Cocoa Cookie - Cookie Run
• Phoenix Wright - Ace Attorney
• Dick Gumshoe - Ace Attorney
• Xenomorph Queen - Alien
• The Midnight Crew - Homestuck
• Kurow - Okamiden
• Amaterasu - Okami
• Cuphead & Mugman - Cuphead
• King Dice - Cuphead
• Omega - Sonic
• Rouge the Bat
• Sonic the Hedgehog
• Silver the Hedgehog
• Kirby
• The Leper - Darkest Dungeon
• Wilson - Don't Starve
• WX-78 - Don't Starve

other:

• No Face - Spirited Away
• Diana - Brawlhalla
• Scarlet - Brawlhalla
• Cassidy - Brawlhalla
• Lord Vraxx - Brawlhalla
• jellyfish

comfort pairings:

• Vampire Cookie/Adventurer Cookie
• Miles Edgeworth/Phoenix Wright
• Waka/Amaterasu
• Jester/Leper
• Diana/Scarlet or Scarlet/Cassidy (or all three!)
• King Dice/Announcer